Regulatory Genomics Lab @Westlake University

Featured publications

(Click here to see the list of all publications)

2024

A fast, scalable and versatile tool for analysis of single-cell omics data
A fast, scalable and versatile tool for analysis of single-cell omics data
Kai Zhang, Nathan R. Zemke, Ethan J. Armand, Bing Ren
Nature Methods  ·  08 Jan 2024  ·  doi:10.1038/s41592-023-02139-9
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2021

A single-cell atlas of chromatin accessibility in the human genome
A single-cell atlas of chromatin accessibility in the human genome
Kai Zhang, James D. Hocker, Michael Miller, Xiaomeng Hou, Joshua Chiou, …, Yang E. Li, Kyle J. Gaulton, Allen Wang, Sebastian Preissl, Bing Ren
Cell  ·  01 Nov 2021  ·  doi:10.1016/j.cell.2021.10.024
Website
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2019

Taiji: System-level identification of key transcription factors reveals transcriptional waves in mouse embryonic development
Taiji: System-level identification of key transcription factors reveals transcriptional waves in mouse embryonic development
Kai Zhang, Mengchi Wang, Ying Zhao, Wei Wang
Science Advances  ·  01 Mar 2019  ·  doi:10.1126/sciadv.aav3262

2017

Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Bingfei Yu, Kai Zhang, J Justin Milner, Clara Toma, Runqiang Chen, …, Shane Crotty, John T Chang, Matthew E Pipkin, Wei Wang, Ananda W Goldrath
Nature Immunology  ·  13 Mar 2017  ·  doi:10.1038/ni.3706

2016

Systematic identification of protein combinations mediating chromatin looping
Systematic identification of protein combinations mediating chromatin looping
Kai Zhang, Nan Li, Richard I. Ainsworth, Wei Wang
Nature Communications  ·  27 Jul 2016  ·  doi:10.1038/ncomms12249